📖 Pyrazolo[3,4-d]pyrimidines, their polycyclic derivatives..

Pyrazolo[3,4-d]pyrimidines are substances that found applications in medical practice (allopurinol), have a number of biological activities: antimicrobial, antiinflammatory, anticancer, etc. Methods of synthesis, including both variants of pyrazole nucleus annulation by pyrimidine ring, pyrimidine nucleus by pyrazole ring, chemical, biological properties of pyrazolo[3,4-d]pyrimidine,, methods of their synthetic usage for the construction of synthetic polycyclic systems have been analyzed, generalized in the review.